Active ingredient: Vitex agnus castus (VAC)

Brand Name: Agnucaston, Agnolyt, Chaste tree, Chasteberry

Drug class: Herbal Medicinal Products

Mechanism of Action:

Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment used in latent hyperprolactinaemia for reducing TRH-stimulated prolactin secretion. VAC normalising a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels

Effect on fertility biomarkers

Vitex is commonly used to treat menstrual irregularities, premenstrual syndrome (PMS), and luteal phase defects, as well as to improve fertility. It can lengthen short cycles by supporting the luteal phase and normalizing ovulation, making it particularly useful for women with irregular cycles or short luteal phases who are planning pregnancy

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Ovulation, Menstrual cycle length

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References:

van Die MD, Burger HG, Teede HJ, Bone KM. Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials. Planta Med. 2013 May;79(7):562-75. doi: 10.1055/s-0032-1327831. Epub 2012 Nov 7. PMID: 23136064.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.