Active ingredient: Trifluoperazine maleate

Brand Name: Stelazine, Trifluoperazine

Drug class: Antipsychotics

Mechanism of Action:

Trifluoperazine maleate is an antipsychotic that works by blocking dopamine (D2) receptors in the brain, helping to manage symptoms of schizophrenia and anxiety.

Effect on fertility biomarkers

Dopamine-blocking action can lead to increased prolactin levels (hyperprolactinemia), which may interfere with fertility by disrupting ovulation. It can also affect cervical mucus production, potentially reducing mucus quality, which could impact sperm movement. In terms of body temperature, trifluoperazine may influence the body’s temperature regulation, leading to potential changes like hyperthermia or hypothermia.

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Ovulation, Mucus, Temperature

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References:

Chang, W. J., Lee, C. H., Liu, K. H., & Lee, C. T. (2006). Antipsychotic-induced hyperprolactinemia. Taiwan Society of Critical Care Medicine Journal, 11(2), 75-83. Retrieved from https://www.tsccm.org.tw/Magazine/Folder/11_2/06.pdf

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.