Active ingredient: Risperidone

Brand Name: Risperdal, Risperdal Consta, and Risperdal M

Drug class: Antipsychotics

Mechanism of Action:

Risperidone is an atypical antipsychotic that primarily acts by blocking dopamine (D2) and serotonin (5-HT2A) receptors.

Effect on fertility biomarkers

Dopamine-blocking effect can lead to increased prolactin levels, causing hyperprolactinemia, which may disrupt menstrual cycles and inhibit ovulation. Additionally, risperidone can influence body temperature regulation, potentially leading to hypothermia.

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Ovulation, Temperature, Menstrual cycle lenght

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References:

Perera MA, Yogaratnam J. De Novo delayed onset hypothermia secondary to therapeutic doses of risperidone in bipolar affective disorder. Ther Adv Psychopharmacol. 2014 Apr;4(2):70-4. doi: 10.1177/2045125313507740. PMID: 24688758; PMCID: PMC3952484. Park YW, Kim Y, Lee JH. Antipsychotic-induced sexual dysfunction and its management. World J Mens Health. 2012 Dec;30(3):153-9. doi: 10.5534/wjmh.2012.30.3.153. Epub 2012 Dec 27. PMID: 23596605; PMCID: PMC3623530.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.