Active ingredient: Propantheline bromide

Brand Name: Pro-Banthine

Drug class: Antispasmodic

Mechanism of Action:

Propantheline Bromide is an antimuscarinic agent primarily used to treat conditions such as excessive sweating (hyperhidrosis), muscle spasms in the stomach, intestines, or bladder, and involuntary urination (enuresis). It is also effective for controlling symptoms of irritable bowel syndrome (IBS) and similar disorders.

Mechanism of Action
Propantheline blocks muscarinic acetylcholine receptors in various smooth muscle tissues (gut, bladder, etc.). Under normal conditions, acetylcholine binds to these receptors, triggering smooth muscle contractions.

Effect on fertility biomarkers

Effects on Temperature Regulation Decreased sweating reduces the body’s ability to cool itself, potentially leading to heat intolerance and hyperthermia. Effects on Mucus Production Reduced mucus production in the respiratory and digestive tracts, leading to dry airways and constipation. Dry mouth is a common side effect due to reduced salivary gland secretion.

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References:

National Center for Advancing Translational Sciences. (n.d.). Propantheline bromide. Inxight Drugs. Retrieved October 15, 2024, from https://drugs.ncats.io/drug/UX9Z118X9F

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.