Active ingredient: Promethazine

Brand Name: Phenergan, Phenadoz

Drug class: Antiemetic Agents

Mechanism of Action:

Promethazine is an antihistamine that works primarily by blocking H1 receptors, which helps reduce allergic reactions, nausea, and vomiting. It also has anticholinergic properties and sedative effects, which can contribute to its efficacy in treating motion sickness and providing sleep aid.

Effect on fertility biomarkers

Neuroleptic malignant syndrome (NMS) is a potential side effect of droperidol. It is characterized by symptoms such as fever, muscle rigidity, and autonomic instability, which can arise following the use of this medication.

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References:

Chan-Tack KM. Neuroleptic malignant syndrome due to promethazine. South Med J. 1999 Oct;92(10):1017-8. doi: 10.1097/00007611-199910000-00015. PMID: 10548178.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.