Active ingredient: Mifepristone

Brand Name: Mifeprex, Korlym, RU486

Drug class: Antiprogestins

Mechanism of Action:

Mifepristone is a progesterone receptor antagonist that blocks the action of progesterone, a hormone crucial for maintaining pregnancy. It is primarily used for medical termination of early pregnancy by causing the detachment of the embryo from the uterine lining

Effect on fertility biomarkers

Mifepristone can disrupt the menstrual cycle by interfering with ovulation and endometrial development. However, its effects are temporary, and normal ovulatory cycles typically resume after discontinuation, restoring fertility.

First
Second
Third
…

Ovulation, Mucus, Temperature

View the chart

References:

Ho PC, Yu Ng EH, Tang OS. Mifepristone: contraceptive and non-contraceptive uses. Curr Opin Obstet Gynecol. 2002 Jun;14(3):325-30. doi: 10.1097/00001703-200206000-00013. PMID: 12032390.

Comments

If you have used this medication and monitored fertility biomarkers, please share your experience.

Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.