Active ingredient: Lithium

Brand Name: Eskalith, Lithobid

Drug class: Bipolar Disorder Agents

Mechanism of Action:

Mechanism of action: Lithium is a mood stabilizer for bipolar disorder, modulating neurotransmitters.

Effect on fertility biomarkers

Effect on fertility: Lithium can cause hypothyroidism, affecting ovulation and fertility. Effect on cycle duration: Hypothyroidism may result in irregular or prolonged cycles, requiring thyroid monitoring. Effect on temperature: Lithium can lower basal body temperature and may lead to neuroleptic malignant syndrome, which affects temperature regulation. Effect on mucus: Side effects like dry mouth may reduce cervical mucus production, potentially affecting sperm movement and fertility.

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Ovulation, Temperature

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References:

Joseph, B.; Nunez, N.A.; Pazdernik, V.; Kumar, R.; Pahwa, M.; Ercis, M.; Ozerdem, A.; Cuellar-Barboza, A.B.; Romo-Nava, F.; McElroy, S.L.; et al. Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study. Brain Sci. 2023, 13, 133. https://doi.org/10.3390/brainsci13010133 Shine, Brian et al. Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data: The Lancet, Volume 386, Issue 9992, 461 - 468

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.