Active ingredient: Juniperis communis

Brand Name: Juniper

Drug class: Herbal Medicinal Products

Mechanism of Action:

Juniperus communis (common juniper) has been traditionally used for various medicinal purposes, including its use as a diuretic, antiseptic, and anti-inflammatory agent. Recent studies have explored its potential antifertility effects.

In laboratory investigations, extracts of Juniperus communis were evaluated for their influence on hormonal activity, particularly their estrogenic, antiestrogenic, progestagenic, and antiprogestagenic effects. The research revealed that Juniperus communis extracts did not exhibit estrogenic or progestagenic activity but demonstrated antiprogestational properties, which account for its antifertility effects.

Effect on fertility biomarkers

By inhibiting progesterone’s action, the extract interferes with the necessary hormonal support for maintaining pregnancy. Progesterone is essential for preparing the uterine lining for implantation and supporting the early stages of pregnancy. The antiprogestational activity of Juniperus communis likely prevents proper implantation or disrupts early pregnancy, leading to reduced fertility. Thus, Juniperus communis may reduce fertility by disrupting normal progesterone function, but its effect on ovulation is less clear. While the extract may not directly inhibit ovulation, its antifertility effect is mainly through preventing successful implantation or the maintenance of early pregnancy due to its antiprogestagenic action

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References:

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.