Active ingredient: Hyoscine butylbromide

Brand Name: Buscopan

Drug class: Antispasmodic

Mechanism of Action:

Mechanism of Action of Buscopan: Buscopan (butylscopolamine) is an antispasmodic that works by inhibiting acetylcholine on muscarinic receptors, leading to the relaxation of smooth muscles, particularly in the gastrointestinal and urogenital tracts.

Effect on fertility biomarkers

Effects on Cervical Mucus and Fertility: Buscopan can inhibit cervical mucus secretion, making the mucus thicker and potentially affecting sperm movement. It also induces cervical priming and dilation, which can be useful before intrauterine procedures. Temperature Effects: Buscopan may cause dryness, reduced sweating, and elevated body temperature.

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Cervix, Mucus, Temperature

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References:

Hadadian S, Fallahian M. Assessing the efficacy of vaginal hyoscine butyl bromide on cervical ripening prior to intrauterine procedures: A double-blinded clinical trial. Int J Reprod Biomed. 2016 Nov;14(11):709-712. PMID: 27981257; PMCID: PMC5153577. Jonsson B, Hammarström M. Autonomic nervous modulation and effects of a prostaglandin synthase inhibitor on human cervical secretion. Hum Reprod. 1993 Aug;8(8):1168-72. doi: 10.1093/oxfordjournals.humrep.a138222. PMID: 8408512.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.