Active ingredient: Hydroxyzine

Brand Name: Atarax, Vistaril

Drug class: Antihystamines

Mechanism of Action:

Hydroxyzine is an antihistamine that works by blocking H1 receptors, preventing the action of histamine, which reduces allergic reactions and provides sedation. It also has anticholinergic properties, contributing to its anxiolytic and sedative effects.

Effect on fertility biomarkers

A common side effect of hydroxyzine is drying of mucous membranes, including the mouth, nose, and throat. This drying effect can extend to cervical mucus, reducing its production and altering its consistency.

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Mucus

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References:

Liu H, Farley JM. Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport. BMC Pharmacol. 2005 Mar 24;5:8. doi: 10.1186/1471-2210-5-8. PMID: 15790419; PMCID: PMC1079883.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.