Active ingredient: Haloperidol

Brand Name: Haldol, Serenace

Drug class: Antipsychotics

Mechanism of Action:

Haloperidol is a typical antipsychotic that works by blocking dopamine (D2) receptors in the brain, reducing symptoms of psychosis. Its dopamine-blocking effects can interfere with the hypothalamic-pituitary-gonadal axis, leading to increased prolactin levels (hyperprolactinemia).

Effect on fertility biomarkers

This rise in prolactin can disrupt menstrual cycles, inhibit ovulation, and reduce fertility in women. Elevated prolactin levels may also cause menstrual irregularities, decreased libido, and potential issues with conception due to hormone imbalances affecting ovulation.

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Ovulation, Temperature, Menstrual cycle lenght

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References:

Bargiota, S. I., Bonotis, K. S., Messinis, I. E., & Angelopoulos, N. V. (2013). The effects of antipsychotics on prolactin levels and women’s menstruation. Schizophrenia Research and Treatment, 2013, Article 502697. https://doi.org/10.1155/2013/502697

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.