Active ingredient: Fluphenazine

Brand Name: Modecate, Modecate Concentrate, Moditen, Prolixin

Drug class: Neuroleptic

Mechanism of Action:

Fluphenazine is a typical antipsychotic that works by blocking dopamine receptors (mainly D2) in the brain, reducing dopamine activity. This helps to alleviate symptoms of schizophrenia and other psychotic disorders, such as hallucinations, delusions, and disorganized thinking. It is used in the treatment of schizophrenia and long-term management of chronic psychosis. Fluphenazine can be administered orally or as a long-acting injectable form.

Effect on fertility biomarkers

Fluphenazine, like other typical antipsychotics, can lead to hyperprolactinemia by blocking dopamine receptors in the hypothalamus, which reduces the inhibitory effect of dopamine on prolactin secretion. Elevated prolactin levels can disrupt the normal regulation of reproductive hormones, leading to menstrual irregularities, such as amenorrhea (absence of periods) or oligomenorrhea (infrequent periods) which may be reflected on fertility tracking charts. These charts could show prolonged cycles, an absence of ovulation (indicated by a lack of typical cervical mucus patterns or temperature shifts), or irregular bleeding. Such disruptions can make it difficult to track fertile days, highlighting the importance of monitoring reproductive health when using antipsychotics.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.