Active ingredient: Ciprofloxacin, Delafloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin, Norfloxacin, Ofloxacin

Brand Name: AveloxFloxinGemifloxacinLevaquinBaxdelaDelafloxacinMoxifloxacinProquin XRFactive

Drug class: Fluoroquinolones antibiotics

Mechanism of Action:

Fluoroquinolones are broad-spectrum antibiotics that work by inhibiting bacterial enzymes DNA gyrase and topoisomerase IV, essential for DNA replication and repair. This interference leads to DNA strand breaks and bacterial cell death. They are commonly used to treat respiratory, urinary, gastrointestinal, and skin infections, particularly those caused by resistant bacteria. However, their use is often limited due to concerns about antibiotic resistance and potential side effects.

Effect on fertility biomarkers

Fluoroquinolones are generally not recommended for use in women planning to become pregnant. This class of antibiotics works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for DNA replication and repair. They are effective against a wide range of infections but have been associated with potential risks during pregnancy. The use of fluoroquinolones during pregnancy may be linked to adverse effects on fetal development, particularly regarding the musculoskeletal system. Some studies suggest that exposure to fluoroquinolones during pregnancy could increase the risk of complications such as joint and cartilage problems in the developing fetus. Women planning pregnancy should consult their healthcare provider for safer alternatives if antibiotic treatment is necessary, as there are other antibiotics considered safer for use during pregnancy.

First 
Second
Third

Mucus

References:

Comments

If you have used this medication and monitored fertility biomarkers, please share your experience.

Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.