Active ingredient: Diclofenac

Brand Name: Voltaren, Cataflam, Cambia, Zorvolex

Drug class: Non-steroidal anti-inflammatory drug (NSAID)

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzymes COX-1 and COX-2, reducing the production of prostaglandins. This decreases inflammation, pain, and fever. Diclofenac is commonly used to treat conditions like arthritis, migraines, and post-surgical pain.

Diclofenac may delay or inhibit ovulation by reducing prostaglandin production, which is crucial for follicle rupture. It can also decrease cervical mucus secretion around ovulation. Since prostaglandins are important for both ovulation and cervical mucus production, the use of diclofenac may impair female fertility by making it harder to track fertile windows and reducing mucus that aids sperm transport. This medication is not recommended for women during the first half of the menstrual cycle due to its potential effects on ovulation and cervical mucus. While diclofenac can cause temporary infertility, this condition is usually reversible, with fertility typically resuming after discontinuation of the drug.

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If you have used this medication and monitored fertility biomarkers, please share your experience.

Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.