Active ingredient: Dehydrobenzperidol

Brand Name: Droperidol, Inapsine, Droleptan, Dridol, Xomolix, Innovar

Drug class: Antiemetic Agents

Mechanism of Action:

Droperidol is an antipsychotic and antiemetic drug that works by blocking dopamine (D2) receptors in the brain, particularly in the chemoreceptor trigger zone, which helps control nausea and vomiting. It also has some alpha-adrenergic blocking effects, leading to sedation and a reduction in blood pressure.

Effect on fertility biomarkers

A significant side effect of droperidol is the risk of neuroleptic malignant syndrome (NMS), which can be suspected if symptoms such as fever (febrile), muscle rigidity, and autonomic instability (e.g., changes in blood pressure, heart rate) develop during treatment.

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References:

So PC. Neuroleptic malignant syndrome induced by droperidol. Hong Kong Med J. 2001 Mar;7(1):101-3. PMID: 11406684.

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.