Active ingredient: Bromocriptine

Brand Name: Cycloset, Parlodel

Drug class: Dopamin receptor agonist

Mechanism of Action:

Bromocriptine is a dopamine agonist that works by stimulating dopamine receptors, which inhibits the release of prolactin from the pituitary gland. It is commonly used to treat conditions like hyperprolactinemia, Parkinson’s disease, and acromegaly. In women, it is often prescribed to manage high prolactin levels that can interfere with reproductive health.

Effect on fertility biomarkers

By lowering prolactin levels, bromocriptine helps restore normal ovulatory function in women with hyperprolactinemia. This can promote regular ovulation and normalize the menstrual cycle, reducing the length of an overly long cycle and improving fertility.

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Ovulation, Menstrual cycl length

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References:

Nillius SJ. Bromocriptine for induction of ovulation in hyperprolactinemic amenorrhea. Acta Eur Fertil. 1984 Mar-Apr;15(2):83-91. PMID: 6475464. Espersen, T., & Thomsen, A. C. (1984). Controlled Study of Bromocriptine and Placebo for Induction of Ovulation in Normoprolactinemic Secondary Amenorrhea. Acta Obstetricia et Gynecologica Scandinavica, 63(8), 715–717. https://doi.org/10.3109/00016348409154670

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Disclaimer: The information provided may not include all possible interactions or side effects of medication. The effects on fertility biomarkers can vary and may depend on the dosage, how long the medication is used, the medical condition, or other factors. This database is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified health professional if you have questions about medications, fertility, or medical conditions.